Researchers from Georgia Tech, Emory, and Yonsei University in Korea have developed Microscale Polystyrene (MP) bottles that would be injectable into patients. Previous types of temperature-controlled microcontainers suffered from a slow loading process, low cargo capacity, or premature release of the drug. These researchers have now developed a new variety of corked “microbottle” for drugs. The cork melts at a defined temperature and releases the bottle’s contents.
Once injected, researchers apply a heating element at the target treatment site. Once the bubbles reach the area of heating, the phase-change material would dissolve and the contents released into the body close to where the drug would be most effective and cause least side effects on the rest of the body.