Explosions and blasts are the primary source of injury commonly faced by American soldiers on the battlefield today. Specifically, internal bleeding in the lungs can lead to irreversible damage and death if not treated immediately, which is often the case for many soldiers. Military hospitals are often miles away blast sites, preventing soldiers from being transported in time to stop and treat internal bleeding.
Researchers from Case Western University and Virginia Tech have developed hemostatic dexamethasone nanoparticles (DNP) that were loaded with corticosteroids and injected to help stop internal clot formation and reduce inflammation in the lungs. In a trial using lab rats, rats who were given the nanoparticles had higher blood oxygen levels, less internal bleeding, and less cell tissue damage than those in the control group.